SubtiBank SubtiBank
Version comparison:

2017-02-27 15:02:04Tue Dec 13 2016 11:16:34 GMT+0100 (CET)

proteinLength

251

geneLength

753

Gene

Phenotypes of a mutant

essential [Pubmed|12682299]

''[[gene|scpA]]'' mutants are not viable on complex medim that allow rapid growth, but they are viable under conditions of slow growth [Pubmed|24440399,24440393]

essential [Pubmed|12682299]

''[[protein|scpA]]'' mutants are not viable on complex medim that allow rapid growth, but they are viable under conditions of slow growth [Pubmed|24440399,24440393]

The protein

[SW|Localization]

nucleoid (Multiple) [Pubmed|16479537]

the [SW|condensin] ([[protein|Smc]])2-[[protein|ScpA]]-[[protein|ScpB]] complex forms two bipolar assemblies on the chromosome, one in each cell half, localization depends on [[protein|ParA]] [Pubmed|24440393,23475963]*the [SW|condensin] ([[protein|Smc]])2-[[protein|ScpA]]-[[protein|ScpB]] complex is loaded by [[protein|ParB]] to ''parS'' centromeric sites adjacent to the replication origin, travels then from the origin to the terminus at rates >50 kb per minute [Pubmed|28154080,24440393,23475963]

nucleoid (Multiple) [Pubmed|16479537]

the [SW|condensin] ([[protein|Smc]])2-[[protein|ScpA]]-[[protein|ScpB]] complex forms two bipolar assemblies on the chromosome, one in each cell half, localization depends on [SW|Spo0J] [Pubmed|24440393,23475963]

Expression and Regulation

[[this]]

References

Original publications

12100548, 12421306, 12065423, 7934830, 16479537, 19450516, 15009890, 11948165, 23353789, 23475963, 22385855, 24440399, 24440393, 25557547, 26253537, 25951515, 26295962, 26725510, 26904953, 28154080

12100548, 12421306, 12065423, 7934830, 16479537, 19450516, 15009890, 11948165, 23353789, 23475963, 22385855, 24440399, 24440393, 25557547, 26253537, 25951515, 26295962, 26725510, 26904953

[SW|Categories] containing this gene/protein

[SW|DNA condensation/ segregation], [SW|essential genes]

The protein

[SW|Interactions]

part of the [SW|condensin] complex [Pubmed|24440399,24440393]

present as stable monomer [Pubmed|22385855]

[[protein|ScpA]]-[[protein|Smc]] [Pubmed|23353789,22385855,12100548]

[[protein|ScpA]]-[[protein|ScpB]] [Pubmed|23353789,12100548]

Expression and Regulation

Operon

''[[protein|scpA]]-[[protein|scpB]]-[[protein|ypuI]]'' [Pubmed|7934830]

Expression and Regulation

Regulation

[[protein|RelA]] dependent downregulation (Class I) during stringent response [Pubmed|11948165]